Clinical Evidence

Fluid Management Makes a Difference

FloPatch and Carotid Doppler Validation

Illustrating the Doppler Starling curve

ultrasound journal

FloPatch is used to simultaneously track surrogates of cardiac preload and output. Two patients in an emergency department have different stroke volume response to a preload augmentation, and are used to illustrate a ‘Doppler Starling curve’ framework.

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Detecting the Change in Total Circulatory Flow

Critical Care Explorations

Blood flow velocity in the common carotid artery tracks changes in total circulatory flow on cardiopulmonary bypass.

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A Novel Spectral Index for Tracking Preload Change


Exploring the ratio of internal jugular-to-carotid artery Doppler power (V/APOWER) as a surrogate for the ratio of the vascular areas of these two vessels.

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Venous excess ultrasound (VExUS) score and
 internal jugular vein Doppler

Intensive Care Medicine Experimental

The venous excess ultrasound (VExUS) score is a multi-organ Doppler approach to assess venous congestion. In this pilot, observational study, we used a wearable Doppler ultrasound to assess the relationship between jugular venous Doppler and the VExUS score under different preload conditions.

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Time cost of ineffective IV fluids in the emergency department

Journal of Intensive Care

In a sample of 53 ED patients, a clinically significant amount of time was spent providing physiologically ineffective IV fluids. Identifying fluid unresponsive patients earlier in their care pathway may represent an avenue to improve ED care efficiency.

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Wearable ultrasound and provocative hemodynamics: a view of the future

Critical Care

Miniature doppler ultrasound devices can provide simultaneous ultrasound of arterial and venous blood flow to infer both cardiac input and output, to help clinicians decide whether patients are fluid non-responsive. Such devices have the potential to generate the slope of the patient’s cardiac function curve in real-time and facilitate a paradigm shift toward personalized therapy in the ICU.

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